Tumour devascularisation as a potential immunotherapeutic strategy.

October 11, 2018
Source: Oncoimmunology. 2018 Oct 11;8(1):e1526614. doi: 10.1080/2162402X.2018.1526614. eCollection 2019.

Authors: T. Buchler, P. Vasek, R. Spisek, P. Skrobanek, V. Horejsi

Complete tumour devascularisation (CTD) is a surgical technique which entails the complete disruption by ligation or cutting of afferent and efferent tumour vasculature which remains in situ. In some animal models, CTD induces immune responses that lead to regression of distant metastases and protective immunity.