Junior Scientist – ADC Discovery Team

At SOTIO Biotech, part of the PPF investment group, we are shaping the future of immunotherapy for cancer patients. It's more than a job. It's a mission with great impact and meaningful goals. 

⏩ We now have an excellent opportunity for a scientist in an early career stage who wants to contribute to translating scientific knowledge into innovative cancer therapeutics ⏪

⏩SOTIO Biotech - YouTube

What is our goal?

Our Antibody-Drug Conjugate (ADC) Discovery team, part of Research and Early Development division, lays the foundation for successful ADC therapies by addressing key scientific and strategic challenges at the outset of the drug development process. In the initial phase we support identification of an optimal target or target pair, prioritization of promising hits, their experimental characterization and validation using scientific literature research, public preclinical data review and in-house in vitro functional assays. Once a preclinical project is launched, we evaluate and optimize antibody properties, ADC efficacy and mechanism of action, providing essential data for clinical candidate selection and regulatory submissions

What working in the ADC Discovery team at Sotio Biotech brings to you?

📌 Purposeful work that can ultimately contribute to improving the lives of cancer patients 

📌 Meaningful work with a direct practical real-world application

📌 Opportunity to learn from experts on various aspects of drug development

📌 Diverse hands-on work using cutting-edge laboratory equipment

📌 Becoming part of a team where we treasure cooperation and open communication

📌 Opportunities for personal and professional growth

Your Activities 🔬

• Design, execute and troubleshoot functional (mainly cell-based) in vitro assays

• Maintain accurate and detailed records of experiments

• Build protocols for the experiments

• Analyze, critically review and interpret collected data

• Prepare reports, presentations and clearly communicate conclusions in internal meetings

• Proactively optimize processes around routine experiments to reduce workload and increase efficiency/speed

• Review relevant scientific literature and other available resources to increase team’s know-how, support the drug development and assay optimization

• Work both independently and as part of a collaborative team to achieve shared goals

Qualification requirements

✅ Master’s degree in cancer biology/cell biology/immunology/molecular biology/pharmacology or related fields

✅ Hands-on experience in cell culture handling, cell-based assays, flow cytometry and molecular biology techniques 

✅ Experience with proliferation, cytotoxicity, drug response assays and/or compound screening is an advantage

✅ A proactive, motivated, open-minded and self-organized person

✅ Ability to conduct data analysis using GraphPad PRISM or equivalent software

✅ Knowledge of the English language on the advanced level is required (written and verbal communication skills)

✅ Flexibility to acquire additional competencies and skillsets as needed

✅ Experience with oncology projects and/or drug development is an advantage

✅ Working with hazardous biological and chemical substances under the appropriate safety measures is part of the job description

✅ Hepatitis B vaccination will be required

📌 Where is our office

• Českomoravská 2532/19b, Libeň, 190 00 Praha 9, Česká republika

Are you ready to take on this challenge and become part of our scientific team? 

The selection process usually involves 2-3 rounds, during which we get to know each other and clarify our expectations. 

We look forward to meeting you! 

SOTIO Biotech team