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NEWS

SOTIO Shares New Preclinical Data on BOXR Platform of Enhanced T Cell Therapies at AACR Annual Meeting

  • BOXR data support platform’s ability to improve on CAR T-cell therapy’s efficacy in solid tumor models;
  • Additional poster investigates utility of PARP inhibitors in combination with immune checkpoint inhibitors

SOTIO Biotech, a clinical-stage immuno-oncology company owned by PPF Group, today presented new preclinical data from the Company’s BOXR platform of enhanced T cell therapies, as well as mechanistic research into the immunostimulatory effects of PARP inhibitors, at the 2024 American Association for Cancer Research (AACR) Annual Meeting.

NEWS

SOTIO Presents New Preclinical Data on Enhanced CAR T-Cell Therapies at AACR Annual Meeting

SOTIO Biotech, a clinical-stage immuno-oncology company owned by PPF Group, today announced it will present new preclinical data at the American Association for Cancer Research (AACR) Annual Meeting taking place April 5-10, 2024, in San Diego, California.
NEWS

SOTIO Presents Preclinical Data from BOXR CAR-T Program and Trial Design of Phase 2 AURELIO-04 Study at SITC Annual Meeting

  • Findings on the mechanism of action from the BOXR CAR-T platform indicate improved metabolic function and preservation of early memory subsets of T cells. 
  • SOTIO anticipates initiating first-in-human DUET-01 trial for lead CAR-T cell therapy candidate, BOXR1030, in coming months.
  • Phase 2 AURELIO-04 combination study of SOT101 and KEYTRUDA® is enrolling patients across multiple solid tumor indications.

SOTIO Biotech, a clinical stage immuno-oncology company owned by PPF Group, presented preclinical data evaluating the mechanism of action and metabolic function of its BOXR T cell platform in a poster presentation at the Society for Immunotherapy of Cancer (SITC) 37th Annual Meeting, taking place in Boston, Massachusetts from November 8-12, 2022. An additional poster was presented on the trial design of AURELIO-04, an ongoing Phase 2 study evaluating the efficacy and safety of SOT101 in combination with pembrolizumab in patients with advanced solid tumors.