Senior Director Pharmacology

The position summary

  • Senior pharmacology role in an advanced and dynamic Biotech company with a focus on antibody-drug conjugate (ADC) development.
  • Reporting to the Chief of Preclinical Development (eventually CSO).
  • Location: Prague (CZ), Basel (CH) or home office with frequent presence in Prague


  • Leading a team of approximately 15 scientists in preclinical drug development.
  • Responsibility for preclinical Pharmacology activities related to the development of ADCs, including antibody discovery, exploration of new antibody-drug conjugates, identification of development candidates, and IND supporting pharmacology.
  • Supervision of in vitro and in vivo studies aimed at the characterization of ADC candidates.
  • Management of activities conducted in house and at Contract Research Organizations.
  • Interaction with other preclinical functions and with cross-functional development teams.
  • Supporting the identification of suitable conjugation technologies (linker / toxin), due diligence and providing recommendations.
  • Following outside ADC development activities, recognition of new industry trends, presentation of SOTIO’s development activities at conferences and other forums.


  • Experience in ADC discovery and early development, knowledge of current linker technologies and toxin developments.
  • Experience in antibody discovery preferred, including antibody generation (animal and recombinant technologies).
  • Leadership experience and capability to continue team building and expansion.
  • Entrepreneurial spirit, good communication skills.
  • Fluent communication in English
  • Ability and willingness to travel frequently

Please note that should you be selected to a final round of selection process, your personal information, including your curriculum vitae, will be, subject to your prior written approval, provided to external personnel agency Genius Search, Heidelberg, Germany.

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