Junior Scientist in Pharmacokinetics

Position Summary:

SOTIO Biotech a. s. offers an exciting career opportunity available in our Research & Early Development, Prague. Bring your diverse experience and work within an exceptional, science-focused environment. You will work with a team focused on the development of IL-15 superagonist and antibody-drug conjugate based novel immunotherapies for the treatment of cancer patients. The Pharmacokinetic team is looking for highly motivated colleagues for Junior Scientist positions to support our preclinical development activities. You as a motivated and pro-active Junior Scientist will be involved in the development and execution of in vitro assays aiming at pharmacokinetic characterization of new molecules.

Key Activities and Responsibilities:

  • Design and execute pharmacokinetic and other related in vitro testing and provide appropriate experimental documentation (protocols, reports, summary presentations in English)
  • Conduct experiments using defined laboratory methods, namely:
    • o ELISA (pharmacokinetic drug profile, anti-drug antibodies detection)
    • o Potency, neutralizing and other functional in vitro cell-based assays
    • o Immunofluorescence (Flow cytometric analyses)
  • Work under aseptic conditions with biological samples (cell cultures)
  • Work in an integrated project team and consult with subject matter experts as necessary


Competences, Skills and Qualification:

  • MSc. degree in Biology, Biochemistry, Pharmacy
  • Experience with cellular in vitro test systems, cell cultures
  • Experience with ELISA method
  • Experience with LC/MS method advantageous
  • Reliability in experimental work and reproducibility, paying high attention to details
  • Ability to learn and adopt new laboratory skills
  • Fluent written and spoken English (B2 level minimum)

Location:

Českomoravská 2532/19b, 190 00 Praha 9, Česká republika

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